26th Annual Ophthalmology Update

24th Annual Distinguished Alumnus Award Lecture


Saturday, March 8, 2014                                     



Farrell Learning and Teaching Center, Robert Emmet Connor Auditorium, First Floor



Washington University is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 



Washington University designates this live activity for a maximum of 5 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.



This live activity is presented by the Department of Ophthalmology and Visual Sciences.



A complete list of commercial supporters will be available at the time of the conference. 



This live activity is being sponsored by Washington University School of Medicine, Continuing Medical Education





Parking will be validated for the North or South Garage. 



The following is a partial list of hotels convenient to the Medical Center.

The Parkway Hotel (314-256-7777), Chase Park Plaza Hotel (314-633-3000).



Please contact Mary Carnoali toll free at 314-362-4418. 

Registration will close on March 1, 2014.



     All speakers, planning committee members, or persons in a position to influence the content of an educational activity, are expected to disclose to the audience any financial interest or other relationship (1) with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services discussed in an educational presentation and (2) with any commercial supporters of the educational activity. Funding and other fiscal relationships with non-profit or government organizations and with non-healthcare-related companies do not have to be disclosed.

     All presenters’ disclosures were reported and are indicated with their presentations.

     Presenters are also expected to openly disclose inclusion of discussion of any off-label, experimental, or investigational use of drugs or devices in their presentations.

     Presentations are expected to be based on evidence that is accepted within the profession of medicine as adequate justification for their indication in the care of patients.  All scientific research should conform to the generally accepted standards of experimental design, data collection and analysis.

     These presentations are the views and experiences of the presenters.  The presenters’ views do not represent the policy or position of Washington University School of Medicine.  Washington University School of Medicine, Continuing Medical Education is the sponsor for CME credits.


COURSE CHAIRS                  

Todd P. Margolis, MD   , PhD                Professor and Head of Ophthalmology & Visual Sciences


Rajendra S. Apte, MD, PhD                 Paul A. Cibis Distinguished Professor, Department of Ophthalmology & Visual Sciences,

Professor Developmental Biology
            Director, Ophthalmology Education



Philip L. Custer, MD                             Professor, Ophthalmology & Visual Sciences

2014 Washington Univ. Ophthalmology Distinguished Alumnus


David Huang, MD, PhD                        Weeks Professor of Ophthalmic Research

                                                Professor of Ophthalmology and Biomedical Engineering

                                                Casey Eye Institute, Oregon Health and Science University





Rajendra S. Apte, MD, PhD                 Paul A Cibis Distinguished Professor, Department of Ophthalmology & Visual Sciences,

Professor Developmental Biology
            Director, Ophthalmology Education


George J. Harocopos, MD                   Associate Professor of Ophthalmology & Visual Sciences,
                                                Pathology, and Immunology; Director of Ophthalmic

Surgery at the John Cochran Veterans Affairs Medical Center


Jonathan Lin, MSTP WUMS II   Ophthalmology Interest Group


John T. Lind, MD                                  Assistant Professor, Ophthalmology & Visual Sciences


Todd P. Margolis, MD   , PhD                Professor and Head of Ophthalmology & Visual Sciences


William A. Peck, MD                             Alan A. and Edith L. Wolf Distinguished Professor of Medicine


Rithwick Rajagopal, MD, PhD  Assistant Professor, Ophthalmology & Visual Science


Gregory P. Van Stavern, MD              Associate Professor, Ophthalmology & Visual Sciences




     This activity reviews recent clinical advances in the diagnosis and management of eye disease, as well as cutting edge basic and translational ophthalmic research.  It is designed for comprehensive and subspecialty ophthalmologists, optometrists, and laboratory-based scientists with the intention of increasing knowledge, improving patient outcomes, improving skills and changing practice performance as well as understanding the disease processes in the eye. 


     Presentations of abnormal conditions may point the physician to include all factors in the differential diagnosis and disease management. The development of pharmacology and surgical techniques broadens treatment options. Solutions will be presented, based on risks and benefits, and economic factors.  The symposium will utilize clinical trial data, case series and encourage audience participation and discussion.  By the conclusion of this activity, participants will be able to specify current concepts in the basic biology, diagnosis, medical treatment, and surgical management of eye diseases encountered by the comprehensive ophthalmologist and sub-specialist.

     At the end of the symposium, each attendee completes a written evaluation.  Questions such as:  How helpful was the information presented in this program; How timely and relevant was the information presented; After attending this program, we will rate the anticipation of changing patient care practices. 


1.  Visual Electrophysiology in Clinical Practice                  

Be aware of the tests available in a Visual Electrophysiology service

Be able to choose which tests to order based upon the clinical question

Recognize the limitations of each test

2.  The Spectrum of Prostaglandin Induced Orbitopathy      

Recognize the findings of prostaglandin induced orbitopathy.

Understand how the side-effects of topical prostaglandin analogs affect eyelid and orbital function.

Improve decision making as to when prostaglandin analogs should be used in the treatment of glaucoma

3.  Ophthalmic Imaging Misadventures                                

Understand the history and evolution of orbital imaging.

Understand where breakdowns in the process of imaging can adversely affect patient care.

Understand the significance of radiation exposure related to medical imaging.

4.  Healthcare in America                                          

Understand the strengths and weakness in the organization and financing of healthcare in American

Understand the major provisions of the Accountable Care Law and their likely impact

Appreciate the major barriers to implementing these major provision and the long range prognosis

5.  Ocular Flora and their Resistance Patterns: A Saint Louis Story           

Know the common bacteria that form the ocular flow

Understand the antibiotic resistance of bacteria in this region

Make internal decisions regarding antibiotic usage in their patients

6. CPC

Discuss the differential diagnosis of a choroidal mass

Understand the utility of immunohistochemistry in establishing the diagnosis, in addition to the caveats, including the concept of “lineage infidelity”

7.  Protecting Photoreceptor Neurons from Inflammation-induced Death in Retinal Detachment   

Understand that inflammation can regulate vision loss

Recognize that rods may be more sensitive to immune responses

Understand mechanisms that cause photoreceptor apoptosis in disease models

8. Structural and Functional OCT                  

List the characteristics of choroidal neovascularization on OCT angiography

Know the effect of glaucoma on optic disc flow index based on OCT angiography

Understand the principles of OCT angiography

9.  Update on Pathogenesis and Treatment of Diabetic Macular Edema     

Recognize novel therapeutic regimens for diabetic macular edema (DME)

List key early steps in the development of DME

Know various imaging modalities used in diagnosis of DME

10. Five things a cataract surgeon needs to know about the retina

When to do cataract surgery in patients with macular degeneration

Consideration for choosing intraocular lenses in patients with retinal disease

Post-operative complications

11.  Diagnosis and Management of HSV Eye Disease

Identify the different presentations of HSV eye disease

Understand the use of antivirals in the management of HSV eye disease

Understand the use of topical corticosteroids in the management of HSV eye disease



7:30     REGISTRATION / Continental Breakfast

8:00     Welcome Remarks

8:10     Visual Electrophysiology in Clinical Practice

                        Gregory P. Van Stavern, MD


The Spectrum of Prostaglandin Induced Orbitopathy

                        Philip L. Custer, MD

8:55     Break

9:15     Ophthalmic Imaging Misadventures

                        Philip L. Custer, MD

9:45     Healthcare in America

William A. Peck, MD

10:30   Ocular Flora and their Resistance Patterns: A Saint Louis Story

                        John T. Lind, MD

11:00   Clinical Pathologic Conference

                        George Harocopos, MD

11:30   Luncheon

12:30   Diagnosis and Management of HSV Eye Disease

                        Todd A, Margolis, MD

12:40   Protecting Photoreceptor Neurons from Inflammation-induced Death in

 Retinal Detachment

                        Jonathan Lin

12:50   Five Things a Cataract Surgeon Needs to Know About the Retina

                        Rajendra Apte, MD, PhD

1:00     Structural and Functional OCT

                        David Huang, MD, PhD

1:45     Update on Pathogenesis and Treatment of Diabetic Macular Edema

                        Rithwick Rajagopal, MD, PhD

2:15     Adjourn

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