Rajendra S. Apte, MD, PhD

Paul A. Cibis Distinguished Professor of Ophthalmology & Visual Science
Professor, Department of Developmental Biology
Professor, Department of Medicine
Professor, Department of Neuroscience Graduate
Program Director of Translational Research
Director, Jeffrey Fort Innovation Fund

Office Phone: 314-747-5262
Alternate Office Phone: 314-362-3315
Patients Seen At: (314) 273-0020 (Washington University Eye Center in South County)
(314) 362-EYES (Washington University Eye Center, Center for Advanced Medicine)

Fax: (314) 362-2420 (Washington University Eye Center in South County)
(314) 362-3725 (Washington University Eye Center, Center for Advanced Medicine)

Email: Apte@vision.wustl.edu

Click here for Dr. Apte lab website


  • Pre-Med: University of Bombay, Bombay, India, 1986
  • Medical Degree: L.T.M. Medical College, University of Bombay, Bombay, India, 1992
  • Ph.D.: Cellular and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, 1997


  • Residency: Ophthalmology, UT Southwestern Medical Center, Dallas, Texas , 2001
  • Fellowship: Retinal Vascular, Wilmer Ophthalmological Institute, Baltimore, Maryland, 2002
  • Fellowship: Vitreoretinal, Wilmer Ophthalmological Institute, Baltimore, Maryland, 2003

Licensure and Board Certification

  • USMLE Certification, 1996
  • Maryland Medical License Number D0057066, expired, 2001
  • American Board of Ophthalmology, 2003-Current
  • Missouri Medical License Number 2003010758, 2003-Current
  • Illinois Medical License Number 36102090, expired, 2003-2012

Honors and Awards

  • Executive Committee Member, The Macula Society
  • Washington University Nominee for the Ellison Foundation New Scholars Award in Aging, 2005

Selected Publications

  1. Silberman DM, Ross K, Sande PH, Kubota S, Ramaswamy S, Apte RS, Mostoslavsky R. SIRT6 Is Required for Normal Retinal Function. PLoS One. 2014 Jun 4;9(6):e98831.
  2. Rao RC, Choudhry N, Apte RS. Subconjunctival bevacizumab for iris neovascularisation - Authors' reply. Lancet Diabetes Endocrinol. 2014 Jun;2(6):450-1.
  3. Stein LR, Wozniak DF, Dearborn JT, Kubota S, Apte RS, Izumi Y, Zorumski CF, Imai S. Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function. J Neurosci. 2014 Apr 23;34(17):5800-15.
  4. Sene A, Apte RS. Eyeballing cholesterol efflux and macrophage function in disease pathogenesis. Trends Endocrinol Metab. 2014 Mar;25(3):107-14.
  5. Rao RC, Choudhry N, Apte RS. Regression of iris neovascularisation secondary to diabetic retinopathy with subconjunctival anti-VEGF therapy. Lancet Diabetes Endocrinol. 2014 Feb;2(2):182.
  6. Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, Laird JM, Sene A, Apte RS, Salomon RG, Hollyfield JG, Perez VL. Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration. Int J Inflam. 2013;2013:503725.
  7. Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema. Ophthalmology. 2013 Sep;120(9):1852-9.
  8. Friedman DS, Holbrook JT, Ansari H, Alexander J, Burke A, Reed SB, Katz J, Thorne JE, Lightman SL, Kempen JH; MUST Research Group. Risk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trial. Ophthalmology. 2013 Aug;120(8):1571-9.
  9. Zhao H, Roychoudhury J, Doggett TA, Apte RS, Ferguson TA. Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013 Aug 7;54(8):5321-31.
  10. Sene A, Khan AA, Cox D, Nakamura RE, Santeford A, Kim BM, Sidhu R, Onken MD, Harbour JW, Hagbi-Levi S, Chowers I, Edwards PA, Baldan A, Parks JS, Ory DS, Apte RS. Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration. Cell Metab. 2013 Apr 2;17(4):549-61.
  11. Dewan V, Lambert D, Edler J, Kymes S, Apte RS. Cost-effectiveness analysis of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 2012 Aug;119(8):1679-84.

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