Thomas A. Ferguson, PhD

Professor, Department of Ophthalmology and Visual Sciences

Office Phone: (314) 362-3745
Lab Phone: (314) 747-5550

Fax: (314) 747-4238


Click here for Dr. Ferguson lab website


  • B.A. in Biology, Kent State University, Kent, Ohio, 1974
  • M.S. in Microbiology, Kent State University, Kent, Ohio, 1976
  • Ph.D. in Microbiology/Immunology, University of Cincinnati College of Medicine, Cincinnati, Ohio, 1982
  • Postdoctoral Training, Yale University School of Medicine, Department of Pathology, Laboratory of Richard K. Gershon

Honors and Awards

  • Robert E. McCormick Scholar, Research To Prevent Blindness, Inc., 1988-89
  • Research to Prevent Blindness Lew Wassermann Award, 2001-2002
  • Designated Fellow of ARVO (FARVO), 2009
  • Research to Prevent Blindness, Senior Scholar Award, 2011-2012

Selected Publications

    Mattapallil MJ, Wawrousek EF, Chan CC, Hui Zhao H, Roychoudhury J, Ferguson TA*, Caspi RR*. The rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes.  Invest Ophthalmol Vis Sci. 53: 2921-7. 2012. PMC3376073. *co-senior authors

    Zhao H, Roychoudhury J, Doggett T, Apte RS, Ferguson TA. Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration. Invest Ophthalmol Vis Sci. 54:4:5321-5231 2013. PMC3738220

    Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, Ablonczy Z, Chan CC, Zhou Z, Green DR, Ferguson TA. Noncanonical autophagy promotes the visual cycle. Cell 154:365-376. 2013. PMC3744125

    Ferguson TA, Green DR. Autophagy and phagocytosis converge for better vision. Autophagy 10:165. 2014. PMC4028322

    LeBlanc PM, Doggett TA, Choi J, Hancock MA, Durocher Y, Frank F, Nagar B, Ferguson TA*, Saleh M*. An immunogenic peptide in the A box of HMGB1 reverses apoptosis-induced tolerance through RAGE. J Biol Chem. 289:7777-7786, 2014. *co-senior authors. PMC3953289. Named “Best of JBC” for 2014

    Zhou Z, Doggett TA, Sene A, Apte RS, Ferguson TA. Autophagy supports survival and phototransduction protein levels in rod photoreceptors. Cell Death Differ. 22:488-98, 2015. PMC4326583

    Doyle SL, López FJ, Celkova L, Brennan K, Mulfaul K, Ozaki E, Kenna PF, Kurali E, Hudson N, Doggett T, et al. IL-18 Immunotherapy for Neovascular AMD: Tolerability and Efficacy in Nonhuman Primates. Invest Ophthalmol Vis Sci. 2015. Aug 1;56:5424-30, PubMed PMID: 26284546

    Zhou Z, Vinberg F, Schottler F, Doggett TA, Kefalov VJ, Ferguson TA. Autophagy Supports Color Vision. Autophagy. 11:1821-32, 2015 PMC4824586.

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