Second Annual David C. Beebe Lecture2/24/2017
Please join us for the Second Annual David C. Beebe Lecture to be held on Monday 6th March 2017 at 4 pm in the Holden Auditorium. This year, the honor has gone to James Funderburgh, PhD, Professor of Ophthalmology and Cell Biology, University of Pittsburgh School of Medicine. The title of the lecture will be 'Crossing the Chasm: Can we really cure corneal blindness using stem cells?'.
Surgery can restore vision in patients with brain injuries12/12/2016
Surgery can restore vision in patients who have suffered hemorrhaging in the eye after a traumatic brain injury, even if the operation doesn’t occur until several months after the injury, according to a small study from vision researchers at Washington University School of Medicine in St. Louis.
Apte and Rajagopal receive RPB awards12/12/2016
Research to Prevent Blindness (RPB) recently awarded Dr. Rajendra Apte and Dr. Rithwick Rajagopal with awards in their latest funding cycle.
Dr. Rajendra Apte received the Nelson Trust Award for Retinitis Pigmentosa.
Dr. Rithwick Rajagopal received the Career Development Award.
Congratulations to both.
To learn more : http://bit/ly/RPBgrant
Cell Reports: Zika Virus Infection in mice causes panuveitis with shedding of virus in tears9/9/2016
Zika virus (ZIKV) is an emerging flavivirus that causes
congenital abnormalities and Guillain-Barre syndrome.
ZIKV infection also results in severe eye disease
characterized by optic neuritis, chorioretinal atrophy,
and blindness in newborns and conjunctivitis
and uveitis in adults. We evaluated ZIKV infection of
the eye by using recently developed mouse models
of pathogenesis. ZIKV-inoculated mice developed
conjunctivitis, panuveitis, and infection of the
cornea, iris, optic nerve, and ganglion and bipolar
cells in the retina. This phenotype was independent
of the entry receptors Axl or Mertk, given that Axl,
Mertk, and Axl Mertk double knockout mice
sustained levels of infection similar to those of control
animals. We also detected abundant viral RNA
in tears, suggesting that virus might be secreted
from lacrimal glands or shed from the cornea. This
model provides a foundation for studying ZIKVinduced
ocular disease, defining mechanisms of viral
persistence, and developing therapeutic approaches
for viral infections of the eye.read more
Peter Lukasiewicz awarded the Brain Boycott Prize8/25/2016
Professor Peter Lukasiewicz has been awarded the prestigious 2016 Brian Boycott Prize for career achievement in retinal neuroscience at the recent FASEB science research conference on retinal neurobiology and visual processing meeting in Keystone, Colorado.
The Federation of American Societies for Experimental Biology (FASEB) meeting on Retinal Neurobiology and Visual Processing is a biannual meeting attracts approximately 200 top-level vision scientists from around the world.
The Brian Boycott Prize is awarded to those researchers who have made a significant contribution to the understanding of the retina and its role in vision processing.
The award is named for Brian Boycott a leading English anatomist, Fellow of the Royal Society, and one of the founders of the field of retinal circuitry in the 1960s. The Boycott Prize was instituted in his honor after his death in 2000.
Founded in 1912, the goal of the FASEB is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to its member societies and collaborative advocacy.
Rajagopal awarded Young Physician-Scientist honor8/22/2016
Rithwick Rajagopal, MD, PhD, an assistant professor of ophthalmology and visual sciences at Washington University School of Medicine in St. Louis, has received a Young Physician-Scientist Award from the American Society for Clinical Investigation.
Rajagopal, working with Clay F. Semenkovich, the Irene E. and Michael M. Karl Professor and director of the Division of Endocrinology, Metabolism & Lipid Research, has found that vision loss from diabetic retinopathy may begin much earlier than previously believed.
Rajagopal received the award in April at a joint meeting in Chicago of the Association of American Physicians, the American Society for Clinical Investigation, and the American Physician Scientists Association.
The award recognizes young physician-scientists whose work is supported by National Institutes of Health (NIH) training grants or similar career-development funding, and who have recently joined the faculty at an academic medical center and have had notable achievements in research.read more
Clinical Tips & Techniques - Anjali Bhorade, MD7/8/2016
Primary Lens extraction for angle closure glaucoma
Anjali Bhorada, MD, St. Louis, discusses lens extraction for the management of angle closure glaucomaread more
Physician-Industry Interactions and Anti–Vascular Endothelial Growth Factor Use Among US Ophthalmologists read more
Steven Bassnett PhD recognized for Lens Research3/28/2016
Steven Bassnett, PhD, of Washington University, St. Louis, Mo., has been named the 2016 Cataract Research Award recipient by the National Foundation for Eye Research for his outstanding work in lens research. The award — a plaque and $2,500 honorarium — will be presented at the Lens Business Meeting during that ARVO 2016 Annual Meeting in Seattleread more
Nerve injury appears to be root of diabetes-related vision loss3/24/2016
Diabetes-related vision loss most often is blamed on blood vessel damage in and around the retina, but new research indicates that much of that vision loss may result from nerve cell injury that occurs long before any blood vessels are damaged.read more
$11.9 million from NIH funds glaucoma study3/1/2016
Dr Kass and Dr Gordon have received four grants totaling $11.9 million from the National Eye Institute at the National Institutes of Health (NIH) to lead a nationwide study to determine whether efforts to prevent or delay the onset of glaucoma have been effective over the course of two decades. The new study is a 20 year follow-up to the Ocular Hypertension Treatment Studyread more
Establishment of the Jeffrey T. Fort Innovation Fund2/4/2016
Dr Rajendra Apte has been named PI on the Jeffrey T. Fort Innovation Fund. This fund has been established through private philanthropy from Mr. Jeffrey T. Fort. It is designed to support Dr. Apte’s research on diseases and conditions of the retina.
Dr Carla Siegfried name first Kolker distinguished professor1/26/2016
Dr. Carla Siegfried has been appointed as the the inaugural Jacquelyn E. and Allan E. Kolker, M.D. Distinguished Professor of Ophthalmology. This professorship was recently made possible by the enormous generosity of Mr. Jeffrey Fort of St. Louis.read more
Dr Lukasiewicz named as new Becker professor1/26/2016
Dr. Peter Lukasiewicz has been named the next Janet and Bernard Becker Professor of Ophthalmology.read more
Dr Kefalov's paper has been recommended as being of special significance in its field12/10/2015
Circadian and light-driven regulation of rod dark adaptation was recommended by Gordon Fain.read more
Adult Human Retinas Can be Rejuvinated and Function After Death; New Use of Donor Tissue for Research, Drug Development, and Retinal Transplantation in the Future.11/13/2015
Several unique procedures and technical applications have been designed, tested, and refined in order to capture transretinal recordings from dissected retina taken from adult human donor eyes.read more
Eye drops could clear up cataracts using newly identified chemical11/5/2015
A chemical that could potentially be used in eye drops to reverse cataracts, the leading cause of blindness, has been identified by a team of scientists from UC San Francisco (UCSF), the University of Michigan (U-M), and Washington University in St. Louis (WUSTL).read more
Eye’s recycling process key to seeing color, bright light10/27/2015
As many of us learned in high school science class, the retina’s rods and cones allow us to see. Rods are for night vision, and cones operate in bright light and allow us to distinguish colors. But although scientists have an idea of what makes rods perform and flourish, they’ve been somewhat in the dark about what keeps cones working and thriving.read more
Congratulations to Dr Mae Gordon for being awarded the Jeffrey & Joyce Myers Lecture Series10/20/2015
Implementing NIH Requirements for Rigorous Experimental Designread more
Bassnett Joins National Advisory Eye Council10/8/2015
The National Eye Institute (NEI), part of NIH, has appointed three new members to the National Advisory Eye Council (NAEC) who are attending their first NAEC meeting as council members today. The NAEC provides guidance on research, training, and other NEI programs.read more
Obituary: David C. Beebe, 70, professor of ophthalmology and visual sciences4/1/2015
David C. Beebe, PhD, the Janet and Bernard Becker Professor of Ophthalmology and Visual Sciences, died at his home in St. Louis on Friday, March 27, 2015, from complications of amyotrophic lateral sclerosis (ALS). He was 70.read more
Dr. Morton Smith to be Honored by SLOS3/30/2015
Dr. Morton Smith will receive the Presidential Award from the St. Louis Ophthalmological Society on April 16, 2015. read more
The human eye can see ‘invisible’ infrared light12/1/2014
Any science textbook will tell you we can’t see infrared light. Like X-rays and radio waves, infrared light waves are outside the visual spectrum.
But an international team of researchers co-led by scientists at Washington University School of Medicine in St. Louis has found that under certain conditions, the retina can sense infrared light after all.read more
Washington People: Todd Margolis10/20/2014
The new head of the School of Medicine’s Department of Ophthalmology and Visual Sciences is pioneering a phone app that could revolutionize the way people are screened for particular eye diseases.read more
Shoss Wins Ophthalmology Times Resident Writer's Award10/15/2014
The winner is Bradley Shoss, MD, of Washington University in St. Louis. His winning entry, "Sniffing Up the Wrong Tree,” is featured in the Oct. 15 issue of Ophthalmology Times. His submission presents a patient who revealed regular intranasal dexmethylphenidate (Focalin) abuse for many years. Based on the presentation of his neurotrophic ulcer combined with this social history, the diagnosis of a pharmacologic-induced neurotrophic keratopathy was made.
Brownson installed as Bernard Becker Professor10/14/2014
Ross C. Brownson, PhD, a leading expert in chronic disease prevention and applied epidemiology at Washington University in St. Louis, was installed as the Bernard Becker Professor in an Oct. 8 ceremony. Brownson holds joint appointments at the Brown School and in Washington University School of Medicine in St. Louis.read more
Corbo receives two research grants9/8/2014
Joseph Corbo, MD, PhD, associate professor of pathology and immunology, of genetics and of ophthalmology and visual sciences, has received a one-year, $25,000 grant from the Center for the Investigation of Membrane Excitability Diseases for research titled “High-Throughput Functional Analysis of Non-Coding Regions Related to Arrhythmias.” read more
Apte receives young investigator award8/21/2014
Rajendra S. Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology & Visual Sciences, is the first recipient of the Presidents’ Young Investigator Award from the American Society of Retina Specialists (ASRS).read more
Proteins critical to wound healing identified8/18/2014
Mice missing two important proteins of the vascular system develop normally and appear healthy in adulthood, as long as they don’t become injured. If they do, their wounds don’t heal properly, a new study shows.read more
Glaucoma drug helps restore vision loss linked to obesity6/25/2014
A new study shows that the eyesight of patients with an unusual vision disorder linked to obesity improves twice as much if they take a glaucoma drug and lose a modest amount of weight than if they only lose weight.
The condition, called idiopathic intracranial hypertension, affects an estimated 100,000 people in the United States. Most are obese women ages 20 to 50.read more
Margolis named Wolff Distinguished Professor of Ophthalmology5/30/2014
Todd P. Margolis, MD, PhD, head of the Department of Ophthalmology and Visual Sciences, has been named the new Alan A. and Edith L. Wolff Distinguished Professor of Ophthalmology at Washington University School of Medicine in St. Louis. Margolis also is ophthalmologist-in-chief at Barnes-Jewish Hospital.read more
Apte receives Camras Award5/2/2014
Rajendra S. Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology & Visual Sciences, is one of three recipients of the 2014 Pfizer Ophthalmics Carl Camras Translational Research Award. The award, given by the ARVO Foundation for Eye Research, recognize researchers ages 45 or younger who have exhibited excellence in research that has led to, or has promise of leading to, clinical applications.read more
Our Washington: serving students3/19/2014
The Kass Family Scholarship, established by Michael Kass, MD, and his wife Charlene Kass, provides more than money to Washington University School of Medicine students. It offers options.
“Debt should not be a factor in determining your future,” Kass said. “I want students to pursue what matters most to them, not what will pay off their debts fastest.”read more
Older adults see better in the doctor’s office12/2/2013
Older adults who have 20/20 vision in their eye doctors’ offices may not see as well at home. A new study from researchers atWashington University School of Medicine in St. Louis suggests dim lighting may be the culprit.read more
School of Medicine, VA ophthalmologist honored at White House11/15/2013
David E. Vollman, MD, was one of 31 finalists for the Samuel J. Heyman Service to America Medal recently honored in a White House ceremony praising the country’s civil servants.
Vollman, an instructor in ophthalmology and visual sciences, treats patients at Washington University School of Medicine and at the John Cochran Veterans Affairs Medical Center in St. Louis. The specific medal for which he was a finalist is the Call to Service Medal, which “recognizes a federal employee whose professional achievements reflect the positive impact that a new generation brings to public service.” Each year, that award recognizes a federal employee under age 35 with less than five years of federal service.read more
Becker memorial set for Nov. 2211/6/2013
Friends and family of Bernard Becker, MD, will gather for a memorial Friday, Nov. 22. Becker, professor emeritus of ophthalmology and visual sciences, died at his home Aug. 28, 2013, at the age of 93.read more
Better Outcomes Through Technology10/8/2013
Exchanging data instantly via the Internet has revolutionized social networking and retail business, and it didn’t take long for medicine to feel the effects. With the touch of a button, you can track your cataract outcomes, get a better understanding of the effects of your anti-VEGF injections and compare your glaucoma treatment results with ophthalmologists around the country. Here are three new Internet-server-based technologies—two of them free—that may be able to help you maximize your results.read more
Students choose labs via scientific ‘speed dating’9/18/2013
Allyson Mayer walked from poster to poster, weighing considerations that will help shape her next few years at Washington University in St. Louis and her career as a biological scientist. Her mission: to pick at least three laboratories for rotations before committing to the one where she will complete her PhD thesis research.read more
Dr. David Vollman nominated for award called the 'Oscars' of the civil service8/18/2013
ST. LOUIS (KSDK) - A local eye doctor is up for a big honor. In October, he'll find out if he's the winner of an award that's called the Oscars of the federal civil service.read more
Recycling in the eye promotes good vision7/18/2013
Recycling isn’t just good for the environment. It’s also good for your eyesight.
Researchers atWashington University School of Medicine in St. Louis and St. Jude Children’s Research Hospital in Memphis, Tenn., have found that good vision depends, at least in part, on a recycling process in the eye that mops up cellular debris and reuses light-sensitive proteins. read more
Vollman follows career of patient care and leadership5/17/2013
As the staff ophthalmologist at the Veterans Health Administration in St. Louis, Mo., Dr. David Vollman, 34, helped to organize a program to track cataract surgeries and record that information in a national Veterans Affairs database.read more
Cholesterol buildup links atherosclerosis and macular degeneration4/2/2013
A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease.
Researchers at Washington University School of Medicine in St. Louis have found that age-related macular degeneration, the leading cause of vision loss in Americans over 50, shares a common link with atherosclerosis. Both problems have the same underlying defect: the inability to remove a buildup of fat and cholesterol.read more
Doctor wins NIH prize for ideas to restore vision2/11/2013
A Washington University retina specialist is one of 10 U.S. scientists selected by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), for innovative projects to improve or restore vision.
The winning proposal from Rajesh C. Rao, MD, a vitreoretinal surgery fellow in the Department of Ophthalmology and Visual Sciences, was chosen from nearly 500 entries. Rao was one of only two retina clinicians to receive the award and the youngest winner in the national competition.read more
Altering eye cells may one day restore vision1/24/2013
Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to scientists atWashington University School of Medicine in St. Louis. read more
Apte to receive Macula Society’s Young Investigator Award12/17/2012
Rajendra S. Apte, MD, PhD, associate professor of ophthalmology and visual science and of developmental biology, will receive the 2013 Young Investigator Award from the Macula Society. Founded in 1977, the society is a forum for new research in retinal vascular and macular diseases, such as diabetic retinopathy and age-related macular degeneration (AMD), the leading cause of vision loss in older adults.read more
Kass named senior associate dean for human research protection8/13/2012
Michael A. Kass, MD, has been appointed to the newly created position of senior associate dean for human research protection at Washington University School of Medicine in St. Louis.
Larry J. Shapiro, MD, executive vice chancellor for medical affairs and dean of the School of Medicine, made the announcement.read more
Tychsen named Hardesty distinguished professor5/23/2012
Pediatric ophthalmologist R. Lawrence Tychsen, MD, has been named the John F. Hardesty, MD, Distinguished Professor of Ophthalmology and Visual Sciences at Washington University School of Medicine in St. Louis.
Chancellor Mark S. Wrighton and Larry J. Shapiro, MD, executive vice chancellor for medical affairs and dean of the School of Medicine, announced the appointment. Tychsen will be installed May 31.read more
Genetic test identifies eye cancer tumors likely to spread3/14/2012
Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver.read more
A closer look at Becker’s special collection2/24/2012
In one way or another, nearly everyone at Washington University School of Medicine has heard of Bernard Becker, MD.
Many use the beautiful Bernard Becker Medical Library or consult rare eye books there from the well-known Becker collection. In the Department of Ophthalmology, which Becker chaired for more than 35 years, faculty members know well his landmark research on glaucoma. One member, David C. Beebe, PhD, is the Janet and Bernard Becker Professor of Ophthalmology and Visual Sciences. But Becker is much more than a portrait in the library.read more
A New View of the Vitreous in Ocular Health and Disease1/1/2012
The vitreous gel doesn’t get much respect. In fact, many surgeons consider it more of a nuisance than a vital component of ocular health. But these attitudes are beginning to change, as a relatively small number of researchers work to define the vitreous gel’s role in protecting against several sight-robbing conditions.read more
Beware of Halloween contact lenses10/26/2011
Some people think it’s cool to give themselves “cat” eyes, “wolf” eyes or really bloodshot eyes for Halloween. That’s possible with decorative contact lenses, but an optometrist at Washington University School of Medicine in St. Louis says beware.read more
More oxygen in eyes of African-Americans may help explain glaucoma risk7/11/2011
Measuring oxygen during eye surgery, investigators at Washington University School of Medicine in St. Louis have discovered a reason that may explain why African-Americans have a higher risk of glaucoma than Caucasians.read more
Gene identified for spread of deadly melanoma11/4/2010
Researchers at Washington University School of Medicine in St. Louis have identified a gene linked to the spread of eye melanoma.
Although more research is needed, the researchers say the discovery is an important step in understanding why some tumors spread (metastasize) and others don’t. They believe the findings could lead to more effective treatments.read more
New procedure aims to save vision of children with eye cancer4/13/2010
An ophthalmologist at Washington University School of Medicine in St. Louis is implanting radioactive discs in the eyes of children with a rare cancer in an attempt to save their vision and their eyes.read more
High eye pressure: monitor or treat?3/8/2010
Most people at risk for developing glaucoma due to high eye pressure do not need treatment, according to a large, multicenter study.
The Ocular Hypertension Treatment Study (OHTS) investigators, led by researchers at Washington University School of Medicine in St. Louis, report in the Archives of Ophthalmology that most patients with high eye pressure but no glaucoma damage can be carefully monitored rather than given eye drops.read more
Touching people’s lives11/4/2009
Age 4 is a big year for many of us. We begin to understand concepts like past, present and future. We learn to take turns, share things and to express anger verbally rather than physically.read more
“I was 4 years old when I decided to be a physician,” she says. “It was before kindergarten, and my only interaction with physicians was my pediatrician. So I wanted to be a pediatrician. And I really never wanted to be anything else.”
Mechanism that helps humans see in bright and low light discovered11/4/2009
Ever wonder how your eyes adjust during a blackout?
When we go from light to near total darkness, cells in the retina must quickly adjust. School of Medicine vision scientists have identified an intricate process that allows the human eye to adapt to darkness very quickly. The same process also allows the eye to function in bright light.read more
Becker receives American Academy of Ophthalmology’s highest award10/27/2009
Bernard Becker, M.D., who headed the Department of Ophthalmology and Visual Sciences at Washington University School of Medicine in St. Louis from 1953 to 1988, is this year’s recipient of the American Academy of Ophthalmology’s highest honor.read more
Pathway in retina found for quickly adapting eyes to darkness3/18/2009
It’s almost time for the movie to start. As you hurry from the lobby into the darkened theater, you may have to stop as the transition from light into darkness renders you temporarily blind. Cells in the eye’s retina must adapt before you can begin to distinguish heads from backs of chairs. As the cells adjust, sight will be restored enough to avoid tripping over a chair or sitting in a stranger’s lap.read more
Less invasive glaucoma surgery allows faster return to normal activity2/25/2009
Surgeons at the Washington University Eye Center and Barnes-Jewish Hospital are among the first to use a new surgical device to treat glaucoma.
Surgery with the device, called a Trabectome, is an outpatient procedure that takes less time to perform and offers a shorter recovery than traditional glaucoma surgery.read more
Cause of vision loss in macular degeneration also plays role in diabetic retinopathy, other retinal diseases10/10/2008
Scientists at Washington University School of Medicine in St. Louis have determined that the same factors play key roles in three different diseases that can lead to blindness. In age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity, abnormal blood-vessel growth threatens vision.
Reporting in the journal PLoS One, Washington University vision scientists say that although the mechanisms are a bit different, all three retinal diseases involve the same immune-system factors.read more
Looking out for the overlooked11/16/2006
As the only boy among nine children, Lawrence Tychsen, M.D., often was asked by his sisters to fix things and figure things out. As Tychsen grew, his hobbies involved designing and building things or taking things apart and fixing them.
It just seemed natural that Tychsen would become a surgeon who fixes vision of children with neurological impairments.read more
Oxygen near lens linked to cataracts in eye surgery patients4/7/2005
Researchers may be a step closer to understanding what causes cataracts and what may help to prevent them.
In a new study published in the American Journal of Ophthalmology, researchers at Washington University School of Medicine in St. Louis report the culprit may be oxygen.read more