Beebe Lab / CV & Publications

Curriculum Vitae - David Cy Beebe

Address:
  • Washington University School of Medicine
  • Department of Ophthalmology and Visual Sciences
  • 660 S. Euclid Ave. Campus Box 8096
  • St. Louis, MO 63110
  • (314) 362-1621 office
  • (314) 747-1588 laboratory
  • (314) 747-1405 fax
  • beebe@wustl.edu
Present Positions:
  • Janet and Bernard Becker Professor of Ophthalmology and Visual Sciences, Washington University
  • Director, Cataract Research Center at Washington University
  • Professor, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO

Education:
1966

B.S. Zoology, University of Rhode Island
1969

M.S. Biomedical Sciences, Brown University
1974

Ph.D. Biology, University of Virginia

Academic Positions:
1995 - 2002

Jules and Doris Stein Research to Prevent Blindness Professor, Dept. Ophthalmology and Visual Sciences, Washington University, St. Louis, MO.
1987 - 1995

Professor and Chairman, Department of Anatomy and Cell Biology, Uniformed Services University of the Health Sciences, Bethesda, MD
1992 - 1995

Professor of Neuroscience, Interdepartmental Neuroscience Program, Uniformed Services University of the Health Sciences, Bethesda, MD
1986 - 1995

Guest Scientist, Henry M. Jackson Foundation for the Advancement of Military Medicine
1975 - 1990

Faculty, Foundation for Advanced Education in the Sciences, NIH, Bethesda, MD
1982 - 1987

Associate Professor, Department of Anatomy, Uniformed Services University of the Health Sciences, Bethesda, MD
1976 - 1982

Assistant Professor, Department of Anatomy, Uniformed Services University of the Health Sciences, Bethesda, MD
1974 - 1976

Staff Fellow, Section on Cellular Differentiation, Laboratory of Molecular Genetics, NICHHD, NIH, Bethesda, MD
1969 - 1970

Assistant Director, Biochemistry Laboratory, Miriam Hospital, Providence, RI
1968 - 1969

Instructor in Biology, Bryant College, Providence, RI

Honors and Awards:

Phi Sigma Honorary Society, University of Rhode Island
1975

Andrew Fleming Award, Outstanding Graduate Student, Dept. of Biology, University of Virginia
1982, 1984

USUHS Outstanding Achievement Award
1984

USUHS Commendable Service Medal
1985 - 1982

Golden Apple, USUHS Class of '85, '82.
1993

Outstanding Instructor, USUHS Class of '95, 1993.
1995 - 2002

Jules and Doris Stein Research to Prevent Blindness Professorship
1997

Alcon Research Award

Past Research Grant Awards:
1974

NIH Postdoctoral Fellowship, Declined
1977 - 1983

USUHS Grant, "Differentiation of Lens Epithelial Cells"
1980 - 1983

NIH Grant, "Development of the Blood Ocular Barriers," EY03429. $122,014. Renewal not requested.
1983 - 1986

NIH Grant, "Factors Controlling Lens Epithelial Cell Differentiation," EY04853. $137,590
1986 - 1988

DoD/USUHS Grant in the program, Medical Applications of Advanced Laser Technology, "Laser Inactivation of Cell Division in the Eye," GM7071. $105,087.
1986 - 1991

NIH Grant, "Factors Controlling Lens Epithelial Cell Differentiation," EY04853. $424,417.
1989 - 1990

Grant from Eygene, Inc., "Regulation of IGF Action in the Eye," $67,500.
1992 - 1998

NIH Grant, "Synthesis, Processing and Degradation of Lens mRNA," EY09179. $604,136. Renewal not requested.
1998 - 2003

NIH Grant, "Development of the Ciliary Epithelium," EY07528 $790,569. Renewal not requested
1996 - 2002

Jules and Doris Stein Research to Prevent Blindness Professorship. $625,000.

Current and Pending Research Grant Funding:
2000 - 2006

NIH Grant, "Factors Controlling Lens Epithelial Cell Differentiation," EY04853.
2006 - 2009

NIH Grant, "Control by Oxygen of Lens Metabolism and Cataract Formation," EY015863
2005 - 2010

NIH Grant, "Research Training Grant in the Vision Sciences," D. Beebe, P.I., EY13360

Professional Associations:
  • American Association of Anatomists
  • American Society for Cell Biology
  • Association for Research in Vision and Ophthalmology
  • Society for Developmental Biology
  • International Society for Developmental Biology
  • International Society for Eye Research

Graduate Students and Postdoctoral Fellows:

  • Richard N. Feinberg, Postdoctoral. Current position, Associate Professor, CMDNJ New Jersey Medical School, Department of Anatomy, Newark, NJ.
  • Carole H. Latker, Postdoctoral. Present position, Scientific Review Administrator, National Institute of General Medical Sciences, NIH, Bethesda, MD.
  • Michael H. Silver, Postdoctoral. Present position, Resident in Psychiatry, The George Washington University, Washington, DC.
  • Judith T. Parmelee, Postdoctoral. Present position, Research Assistant Professor, Department of Clinical Neuroscience, Rhode Island Hospital and Brown University, Providence, RI.
  • George A. Hyatt, former graduate student, current high school teacher, Massachusetts.
  • Carmelann Zintz, graduate student and postdoctoral, currently Research Associate, Baylor University School of Medicine, Houston, TX
  • Eric Reichman, former graduate student, currently a medical student, Medical College of Wisconsin.
  • Elizabeth D. Kaplan, former graduate student, currently postdoctoral fellow in the laboratory of Dr. Joram Piatigorsky, LMDB, NEI, NIH, Bethesda, MD.
  • Xuan Li, graduate student, currently Staff Scientist at OriGene Technologies, Rockville, MD.
  • Steven Bassnett, former postdoctoral, currently Associate Professor, Dept. Ophthalmol. and Visual Sci., Washington Univ. Sch. Med
  • Rita Dhawan, former Research Associate.
  • Timothy Schoen, former graduate student, currently Director of Grants & Awards, Foundation For Fighting Blindness
  • Ronald LaBiche, former postdoctoral, currently Res. Assistant Professor, Dept. Ob-Gyn, USUHS, Bethesda, MD
  • Jay D. Potts, Assistant Professor, Dept. Developmental Biology and Anatomy, University of South Carolina Medical School, Columbia, SC
  • Toshiyuki Nagamoto, MD, PhD, former Postdoctoral Fellow, Assistant Professor, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.
  • Jian-Xin Huang, Ph.D., Research Associate, currently M.D. in private practice.
  • Yogendra Sharma, Ph.D., Visiting Scientist, currently Staff Scientist, Centre for Cellular and Molecular Biology, Hyderabad, India.
  • Elena Frolova, Ph.D., Postdoctoral Fellow, currently Assistant Professor, University of Texas at Galveston, Depts. Microbiology and Ophthalmology
  • Shui Ping Wang, Ph.D., Research Associate, currently Staff Scientist in a biotechnology company
  • Oleg Vasiliev, Ph.D., current Visiting Scientist
  • Ying-Bo Shui, MD. Ph.D., current Senior Scientist
  • Claudia Garcia, Ph.D., current Research Associate
  • Xiaohui Wang, Ph.D., current Research Associate
  • Ramya Rajagopal, current graduate student

Professional Activities:
1982-3

President, Faculty Assembly and Faculty Senate.
1978-80

Vice President, Faculty Assembly.
1977-8, 1986-7

Secretary-Treasurer, Faculty Assembly.
1978-9

Chairman, Ad Hoc Committee on Promotions and Tenure.
1984-7

Committee on Appointments, Promotion and Tenure.
1982-4

Radiation Safety Committee.
1981-4

Research Merit Review Committee.
1979-81

Curriculum Committee.
1976-81

Graduate Education Committee, Chairman, 1980-1.
1979 - 1982

Biohazards, Controlled Substances & Dangerous Drugs Committee, Member, Recombinant DNA Augmentee, 1983 - 95.
1986-7

Ad Hoc Committee on Tenure Policy Review.
1986 - 1989

Medical Applications of Advanced Laser Technology, Grant Merit Review Committee.
1990

Chairman, Basic Science Chairman's Committee.
1988, 1990, 1993

Dean's Executive Advisory Committee.
1992-3

LCME Site Visit Research Committee, Chairman.
1993-94

Chairman, Ad Hoc Committee on Reorganization of the Graduate Program.
1998-9

Search Committee for Head, Dept. Ophthalmol Vis. Sci., Washington Univ.
2002 - 2004

Course Master, Developmental Biology, Division of Biology and Biomedical Sciences, Washington University.

Departmental Activities (USUHS):

  • Head, Departmental Graduate Program
  • Head, Departmental Seminar Committee
  • Member, Departmental Graduate Committee
  • Head, Departmental Computer Committee
  • Member, Departmental Library Committee

Bibliography: (refereed papers):

  • Beebe, D. C. & Piatigorsky, J. (1976). Differential synthesis of crystallin and non crystallin polypeptides during lens fiber differentiation in vitro. Exp. Eye Res. 22, 237 249.
  • Beebe, D. C. & Piatigorsky, J. (1976). Electrophoretic differences between calf and embryonic chick alpha crystallin polypeptides. Exp. Eye Res. 23, 83 88.
  • Beebe, D. C. & Piatigorsky, J. (1977). The control of delta crystallin gene expression during lens cell development: Dissociation of cell elongation, cell division, delta crystallin synthesis, and delta crystallin mRNA accumulation. Dev. Biol. 59, 174 182.
  • Beebe, D. C., Feagans, D., Blanchette Mackie, J., and Nau, M. (1979). Lens epithelial cell elongation in the absence of microtubules: Evidence for a new effect of colchicine. Science 206, 836 838.
  • Beebe, D., Feagans, D., & Jebens, H. A. H. (1980). Lentropin: A factor in vitreous humor which promotes lens fiber differentiation. Proc. Nat'l Acad. Sci. USA 77, 490 493.
  • Beebe, D. C. & Piatigorsky, J. (1981). Translational regulation of delta crystallin synthesis during lens development in the chicken embryo. Dev. Biol. 84, 96 101.
  • Beebe, D. C. & Feagans, D. (1981). A tissue culture system for studying lens cell differentiation. Vision Res. 21, 113 118.
  • Ostrer, H., Beebe, D. C., & Piatigorsky, J. (1981). Beta crystallin mRNAs; differential distribution in the chicken lens. Dev. Biol. 86, 403 408.
  • Beebe, D. C., Compart, P. J., Johnson, M. C., Feagans, D. E., & Feinberg, R. N. (1982). The mechanism of cell elongation during lens fiber differentiation. Dev. Biol. 92, 54 59.
  • Zelenka, P. S., Beebe, D. C., & Feagans, D. (1982). Transmethylation of phosphatidyl- ethanolamine: An initial event in chicken lens fiber cell differentiation. Science 217, 1265 1267.
  • Feinberg, R. N. & Beebe, D. C. (1983). Hyaluronate and vasculogenesis. Science 220, 1177 1179.
  • Johnson, M. C. & Beebe, D. C. (1984). Growth, synthesis and regional specialization of the embryonic chicken lens capsule. Exp. Eye Res. 38, 579 592.
  • Latker, C. H. & Beebe, D. C. (1984). Developmental changes in the blood ocular barriers in chicken embryos. Exp. Eye Res. 39, 401 414.
  • Hejtmancik, J. F., Beebe, D. C., Ostrer, H., and Piatigorsky, J. (1985). Delta and beta crystallin mRNA levels in the embryonic and post-hatched chicken lens: Temporal and spatial changes during development. Dev. Biol. 109, 72 81.
  • Beebe, D. C., Latker, C. H., Jebens, H. A. H., Johnson, M. C., Feagans, D. E., Feinberg, R. N. (1986). Transport and steady state concentration of plasma proteins in the vitreous humor of the chicken embryo: Implications for the mechanism of eye growth during early development. Dev. Biol. 114, 361 368.
  • Feinberg, R. N., Latker, C. H., & Beebe, D. C. (1986). Localized vascular regression during limb morphogenesis in the chicken embryo. I. Spatial and temporal changes in the vascular pattern. Anat. Rec. 214, 405 409.
  • Latker, C. H., Feinberg, R. N., & Beebe, D. C. (1986). Localized vascular regression during limb morphogenesis in the chicken embryo. II. Morphological changes in the vasculature. Anat. Rec. 214, 410 417.
  • Zintz, C. & Beebe, D. C. (1986). Morphological and cell volume changes in the rat lens during the formation of radiation cataracts. Exp. Eye Res. 42, 43 54.
  • Beebe, D. C., Silver, M. H., Snellings, K. L., Van Wyk, J. J., Svoboda, M. E. & Zelenka, P. S. (1987) Lentropin, a protein that controls lens formation, is related functionally and immunologically to the insulin like growth factors. Proc. Nat'l Acad. Sci. USA 84, 2327-2330.
  • Nath, P., Getzenberg, R., Beebe, D., Pallansch, L., and Zelenka, P. (1987). c myc mRNA is elevated as differentiating lens cells withdraw from the cell cycle. Exp. Cell Res. 169, 215-222.
  • Parmelee, J. and Beebe, D. C. (1988). Decreased membrane permeability to potassium is responsible for the cell volume increase that drives lens fiber cell elongation. J. Cell. Physiol. 134, 491-496.
  • Beebe, D. C. and Cerrelli, S. (1989). Cytochalasin prevents cell elongation and increases potassium efflux from embryonic lens epithelial cells: Implications for the mechanism of lens fiber cell elongation. Lens and Eye Tox. Res. 6, 589-601.
  • Beebe, D. C., Parmelee, J. T. and Belcher, K. S. (1990) Cell volume regulation in lens epithelial cells. J. Cell. Physiol. 143, 455-459.
  • Bassnett, S., Reinisch, L. and Beebe, D. C. (1990). Intracellular pH measurement using single excitation/dual emission fluorescence ratios. Am. J. Physiol. 258, C171-C17.
  • Bassnett, S. and Beebe, D. C. (1990) Localization of insulin-like growth factor-1 receptors in the embryonic chicken eye. Invest. Ophthalmol. Vis. Sci. 31, 1637-1643.
  • Reichman, E. F. and Beebe, D. C. (1990) Acetylcholinesterase activity as a marker for the development of the ciliary epitheliun in the chicken embryo. Exp. Eye Res. 51, 249-255.
  • Li, X. and Beebe, D. C. (1991) Messenger RNA stabilization in chicken lens development: A reexamination. Dev. Biol. 146, 239-241.
  • Zintz, C. B. and Beebe, D. C. (1991) Rapid re-amplification of PCR products purified in low-melting-point agarose gels. Biotechniques 11, 158-162.
  • Bassnett, S., Becker, T. M. and Beebe, D. C. (1992) Ion concentrations, fluxes and electrical properties of the embryonic chicken lens. Exp. Eye Res. 54, 215-224
  • Hyatt, G. A. and Beebe, D. C. (1992) Use of a double label method to detect rapid changes in the proliferative activity of embryonic cells: The relationship between lens fiber differentiation and the cell cycle. J. Histochem. Cytochem. 40, 619-627.
  • Reichman, E. F. and Beebe, D. C. (1992) Cellular dynamics of the ciliary epithelium in the embryonic chicken eye. Developmental Dynamics. 193, 125-135.
  • Schoen, T. J., Beebe, D. C., Clemmons, D. R., Chader, G. J., Waldbillig, R. J. (1992) Insulin-like growth factor binding proteins in vitreous and serum: A model for independent developmental regulation in extravascular and vascular compartments. Endocrinology 131, 2846-2854.
  • Bassnett, S. and Beebe, D. C. (1992) Coincident loss of mitochondria and nuclei during lens fiber cell differentiation. Developmental Dynamics 194, 85-93.
  • Hyatt, G. A. and Beebe, D. C. (1993). Evidence that an embryo-specific serum mitogen and inhibitors of lens proliferation and differentiation regulate lens growth and polarity in the chicken embryo. Development 117, 701-709.
  • Dhawan, R. R. and Beebe, D. C. (1993) Differential expression of collagen IX isoforms during development of the embryonic chicken eye. Invest. Ophthalmol. Vis. Sci. 35, 470-478.
  • Li, X. and Beebe, D. C. (1993) Transcriptional control of ?-crystallin gene expression in the chicken embryo lens: Demonstration using a new method for measuring mRNA metabolism. Mol. Cell Biol., 13, 3282-3290.
  • Potts, J.D., Harocopos, G.J., Beebe, D.C. (1993). Identification of receptor tyrosine kinases in the embryonic chicken lens. Curr. Eye Res. 12, 759-763.
  • Bassnett, S., Kuszak, J. R., Reinisch, L., Brown, H. G. and Beebe, D. C. (1994) Intercellular communication between epithelial and fiber cells of the eye lens. J. Cell Sci., 107, 799-811.
  • Beebe, D.C. (1994). Homeobox genes and vertebrate eye development. Invest. Ophthalmol. Vis. Sci. 35, 2897-2900.
  • Potts, J.D. Bassnett, S., Kornacker, S., and D.C. Beebe. (1994). Expression of platelet-derived growth factor receptors in the developing chicken lens. Invest. Ophthalmol. Vis. Sci. 35, 3413-3421.
  • Potts, J.D., Bassnett, S. and Beebe, D.C. (1995). Expression of transforming growth factor-? (TGF?) in the embryonic avian lens coincides with the presence of mitochondria. Developmental Dynamics. 203, 317-323.
  • Schoen, T.J. Mazuruk, K., Waldbillig, R.J., Potts, J. Beebe, D.C. Chader, G.J. and Rodriguez, I.R. (1995). Cloning and characterization of a chick embryo cDNA and gene for IGF-binding protein-2. J. Mol. Endocrinol. 14, 91-100.
  • Schoen, T.J., Bondy, C.A., Zhou, J., Dhawan, R., Mazuruk, K., Arnold, D.R. Rodrigiguez, I.R., Waldbillig, R.J., Beebe, D.C., and Chader, G.J. (1995) In-situ localization and differential expression of insulin-like growth factor binding protein-2 in developing chick ocular tissues. Invest. Ophthalmol. Vis. Sci. 36;2652-2662
  • Beebe, D.C. and Masters, B.R. (1996) Cell lineage and the differentiation of corneal epithelial cells. Invest. Ophthalmol. Vis. Sci., 37, 1815-1825.
  • Kostick, A.M.P., Romanchuk, K.G. and Beebe, D.C. (1996). Anterior pyramidal cataract in Ehlers-Danlos Syndrome. Can. J. Ophthalmol. 31;133-136.
  • Dhawan, R.R. and Beebe, D.C. (1997). Isolation and expression of homeobox genes from the embryonic chicken eye. Molecular Vision, 3;7-15.
  • Fitch, J.M., Fini, M.E., Beebe, D.C., Linsenmayer, T.F. (1998). Collagen type IX and developmentally regulated swelling of the avian primary corneal stroma. Dev. Dyn. 212;27-37.
  • Beebe D.C. (1998). Nuclear cataracts and nutrition: hope for intervention early and late in life. Invest Ophthalmol Vis Sci 1998 Aug;39(9):1531-4
  • Harocopos, G., Alvares, K., Kolker, A. and Beebe, D. (1998).Human age-related cataract and lens epithelial cell death. Invest. Ophthalmol. Vis. Sci., 39:2696-706.
  • Potts, JD., Kornacker, S. and Beebe, D.C. (1998). Activation of the Jak-STAT signaling pathway in embryonic lens cells. Dev. Biol., 204:277-92.
  • Beebe, D.C. and Coats, J.M. (2000). The Lens Organizes the Anterior Segment: Specification of Neural Crest Cell Differentiation in the Avian Eye. Dev. Biol. 220:424-431.
  • Frolova, E. and Beebe, DC. (2000) The expression of a Deltex homologue in the chicken embryo. Mech Dev. 92:285-289.
  • Nagamoto, T, Eguchi, G, and Beebe, DC. (2000). Alpha-smooth muscle actin expression in cultured lens epithelial cells. Invest. Ophthalmol. Vis. Sci. 41:1122-1129.
  • Lim DJ, Rubenstein AE, Evans DG, Jacks T, Seizinger BG, Baser ME, Beebe D, Brackmann DE, Chiocca EA, Fehon RG, Giovannini M, Glazer R, Gusella JF, Gutmann DH, Korf B, Lieberman F, Martuza R, McClatchey AI, Parry DM, Pulst SM, Ramesh V, Ramsey WJ, Ratner N, Rutkowski JL, Ruttledge M, Weinstein DE. (2000). Advances in Neurofibromatosis 2 (NF2): A Workshop Report. J Neurogenet. 14(2):63-106.
  • Beebe DC, Vasiliev O, Guo J, Shui YB, Bassnett S. (2001). Changes in adhesion complexes define stages in the differentiation of lens fiber cells. Invest Ophthalmol Vis Sci. 42(3):727-734.
  • Belecky-Adams, T., Adler, R. and Beebe, D.C. (2002). Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development, 129(16):3795-3802.
  • Huang, J-X, Feldmeier, M, Shui, Y-B, and Beebe, D. (2003). Evaluation of fibroblast growth factor signaling during lens fiber cell differentiation. Invest Ophthalmol Vis Sci. 44:680-90.
  • Shui, Y-B, Wang, X, Hu, JS, Wang, S-P, Garcia, CM, Potts, JD, Sharma, Y, Beebe, DC. (2003). Vascular endothelial growth factor expression and signaling in the lens. Invest Ophthalmol Vis Sci. 44:3911-3919.
  • Harocopos, GJ, Shui, M.D., Y-B, McKinnon, M., Holekamp, NM, Gordon, MO and Beebe, DC. (2004). The importance of vitreous liquefaction in age-related cataract. Invest. Ophthalmol. Vis. Sci. 45:77-85.
  • Frolova, EI, Fokina, VM, Beebe, DC. (2004). The expression pattern of opticin during chicken embryogenesis. Gene Expr Patterns., 4:335-338.
  • Wang, X, Garcia, CM, Shui, YB, Beebe, DC. (2004). Expression and regulation of ?-, ß-, and ?-crystallins in mammalian lens epithelial cells. Invest. Ophthalmol. Vis. Sci. 45:3608-3619.
  • Beebe, D, Guo, J, Garcia, C, Wang, X, Rajagopal, R, Feldmeier, M, Kim, J, Chytil, A, Moses, H, Ashery-Padan, R., Rauchman, M. (2004). Contributions by members of the TGFß superfamily to lens development. Int. J. Dev. Biol. 48:845-856.
  • Holekamp, NM, Shui, Y-B, Beebe, D. (2005). Vitrectomy surgery increases oxygen exposure to the lens: a possible mechanism for nuclear cataract formation. Am. J. Ophthalmol. 139:302-310.
  • Garcia, C, Zhao, H, Yu, K, Ashery-Padan, R, Ornitz, D, Robinson, M, Beebe, D. (2005). Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation. Dev. Dyn. 233:515-27.
  • Holekamp, NM, Shui, Y-B, Beebe, DC. (2005). Lower intraocular oxygen tension in diabetics: possible contribution to decreased incidence of nuclear sclerotic cataract. Am J Ophthalmol. In press.
  • Shui, Y-B, J-J Fu, C Garcia, LK Dattilo, R Rajagopal, S McMillan, G Mak, NM Holekamp, A Lewis and DC Beebe (2006). Oxygen distribution in the rabbit eye and oxygen consumption by the lens. Invest Ophthalmol Vis Sci In press.
  • Vasiliev, O. Rhodes, S. and Beebe, D.C. Identification and regulation of HOP, an atypical homeobox gene expressed late in lens fiber cell differentiation. Submitted.

Bibliography (non-refereed papers, reviews and book chapters):

  • Piatigorsky, J., Beebe, D. C., Zelenka, P., Milstone, L. M., & Shinohara, T. (1976). Regulation of delta crystallin gene expression during development of the embryonic chick lens. INSERM 60, 85 112.
  • Beebe, D. C., Johnson, M., Feagans, D., & Compart, P. (1981) The mechanism of cell elongation during lens fiber differentiation. In Hilfer, S. R. & Sheffield, J., Ocular Size and Shape During Development (79 98). New York, NY: Springer Verlag.
  • Piatigorsky, J., Chepelinsky, A. B., Hejtmancik, J. F., Borras, T., Das, G. C., Hawkins, J. W., Zelenka, P. S., King, C. R., Beebe, D. C., and Nickerson, J. M. (1984) Expression of crystallin gene families in the differentiating eye lens, Molecular Biology of Development (331 349) Alan R. Liss, Inc.
  • Beebe, D. C. (1985) Ocular growth and differentiation factors. In Guroff, G., Growth and Maturation Factors (37 76). New York: John Wiley & Sons.
  • Beebe, D., Snellings, K., Silver, M., & Van Wyk, J. (1986) Control of lens cell differentiation and ion fluxes by growth factors. In Slavkin, H. C., Prog. Dev. Biol. (365 369). New York: Alan R. Liss, Inc.
  • Beebe, D. C. (1986). The development of the ciliary body: A brief review. Trans. Ophthalmol. Soc. UK 105, 123 130.
  • Beebe, D. C. (1988). Discussion summary: Growth factors in the eye. in Piatigorsky, J., Zelenka, P.S. and Shinohara, T., Molecular Biology of the Eye: Genes, Vision and Ocular Disease. Alan R. Liss, Inc. 457-60.
  • Beebe, D. C. (1992). The control of lens growth: Relationship to secondary cataract. Acta Ophthalmologica (Suppl.) 205, 53-57.
  • Beebe, D. C. (2003). Adler's Physiology of the Eye, 10th Ed. Section 3, "The Lens." Kaufman, P. and Alm, A., Eds. Mosby, St. Louis, MO.
  • Bassnett, S and Beebe, D (2004). Lens Fiber Differentiation. Development of the Ocular Lens. F. J. Lovicu and M. L. Robinson, eds.

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