Kefalov Lab / CV & Publications
Curriculum Vitae - Vladimir Kefalov
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Present Positions: |
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Education: |
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1999-2005 |
Postdoctoral Fellow, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland. |
1993-1999 |
Ph.D. in Cellular Biophysics, Department of Physiology, Boston University School of Medicine, Boston, Massachusetts. |
1988-1993 |
M.Sc. in Physics, Department of Physics, Sofia University, Sofia, Bulgaria. |
Academic Positions: |
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2005 - |
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Additional Training: |
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2005 |
Cell & Developmental Biology of Xenopus course at Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. |
1999 |
Methods in Computational Neuroscience course at the Marine Biological Laboratory, Woods Hole, Massachusetts. |
1990-1992 |
Research Technician: Visual Perception Group, Institute of Human Physiology, Bulgarian Academy of Sciences, Sofia, Bulgaria. |
Grants and Awards: |
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2006 |
Research to Prevent Blindness Career Development Award |
2005 |
Karl Kirchgessner Foundation Vision Research Grant |
2005 |
FASEB Award for talk presentation (Biology and Chemistry of Vision research conference) |
2001-2002 |
Visual Neuroscience Training Grant, Johns Hopkins University School of Medicine. |
1999 |
National Eye Institute Travel Grant (ARVO). |
1999 |
Boston University Student Achievement Day - First prize. |
1998 |
Boston University Student Research Fellowship - First prize. |
1998 |
Boston University Student Achievement Day - Second prize. |
Invited Talks: |
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June 2005 |
FASEB Summer Research Conference: The biology and chemistry of vision, Tucson, Arizona. |
November 2004 |
University of Texas Southwestern Medical Center, Dallas, Texas. |
October 2004 |
Yale University School of Medicine, New Haven, Connecticut. |
April 2004 |
Eight Annual Vision Research Conference, Ft. Lauderdale, Florida. |
May 2003 |
Seventh Annual Vision Research Conference, Ft. Lauderdale, Florida. |
June 2001 |
FASEB Summer Research Conference: The biology and chemistry of vision, Tucson, Arizona. |
March 1999 |
Medical University of South Carolina, Charleston, South Carolina. |
August 1998 |
University of Cambridge, Cambridge, UK. |
August 1998 |
King's College, London, UK. |
November 1997 |
Schepens Eye Research Institute, Boston, MA. |
Publications:
- Kefalov, V. J., Estevez, M. E., Kono, M., Goletz, P. W., Crouch, R. K., Cornwall, M. C., and Yau, K. W. (2005). Breaking the Covalent Bond- A Pigment Property that Contributes to Desensitization in Cones. Neuron 46, 879-890.
- Kefalov, V.J., Fu, Y., Marsh-Armstrong, N., and Yau, K.-W. (2003). Role of visual pigment properties in rod and cone phototransduction. Nature. 425, 526-531.
- Crouch, R.K., Kefalov, V.J., Gartner, W., and Cornwall, M.C. (2002). Use of retinal analogues for the study of visual pigment function. Methods Enzymol 343, 29-48.
- Kefalov, V.J., Crouch, R.K., and Cornwall, M.C. (2001). Role of noncovalent binding of 11-cis-retinal to opsin in dark adaptation of rod and cone photoreceptors. Neuron 29, 749-55.
- Corson, D.W., Kefalov, V.J., Cornwall, M.C., and Crouch, R.K. (2000). Effect of 11-cis 13-demethylretinal on phototransduction in bleach-adapted rod and cone photoreceptors. J Gen Physiol 116, 283-97. (Journal Cover)
- Cornwall, M.C., Jones, G.J., Kefalov, V.J., Fain, G.L., and Matthews, H.R. (2000). Electrophysiological methods for measurement of activation of phototransduction by bleached visual pigment in salamander photoreceptors. Methods Enzymol 316, 224-52.
- Kefalov, V.J., Cornwall, M.C., and Crouch, R.K. (1999). Occupancy of the chromophore binding site of opsin activates visual transduction in rod photoreceptors. J Gen Physiol 113, 491-503.
- Davi, M., Yakimoff, N., Bocheva, N., Kefalov, V.J. (1993). The relative roles of vertices and sides in determining perceptual centers within shapes. Acta Neurobiol Exp (Wars) 53, 367-375.
Abstracts:
- Kefalov, V.J., Fu, Y., Su, C.-Y., Marsh-Armstrong, N., Schnetkamp, P.P.M., and Yau, K.-W. (2004). Functional expression of human rod and cone Na/Ca-K exchangers in Xenopus laevis rods. IOVS 45: 1344 (poster).
- Fan, J, Rohrer, B., Chen, C.K., Kefalov, V.J., Yau, K.-W., and Crouch, R.K. (2004). Opsin phosphorylation in RPE65-/- mice reduces retinal degeneration. Eight Annual Vision Research Conference, Ft. Lauderdale, Florida (poster).
- Kefalov, V.J., Fu, Y., Marsh-Armstrong, N., and Yau, K.-W. (2002). Functional expression of human red cone opsin in Xenopus laevis rods. IOVS 43: 1834 (paper).
- Fu, Y., Kefalov, V.J., and Yau, K.-W. (2002). Study of cone pigment function with a transgenic mouse model. IOVS 43: 1962 (paper).
- Kefalov, V.J., Crouch, R.K., Cornwall, M.C., and Yau, K.-W. (2001). Dark exchange of chromophore in amphibian red cones. IOVS 42: 639 (paper).
- Corson, D.W., Kefalov, V.J., Crouch, R.K., Rosebrock, C., and Cornwall, M.C. (1999). Opposite effects of activity of the transduction cascade in bleached rods and cones following treatment with 11-cis 13-demethyl retinal. IOVS 40: 1261 (poster).
- Kefalov, V.J., Crouch, R.K., and Cornwall, M.C. (1999). Transient activation of transduction by 11-cis retinal during pigment regeneration in bleach-adapted rods. IOVS 40: 1965 (paper).
- Engbretson, G.A., Kefalov, V.J., Cameron, D.A., Cornwall, M.C., Knox. B.E., and Barlow, R.B. (1999). Responses and microspectrophotometry of Xenopus rods expressing GFP and mutant bovine rhodopsin. IOVS 40: 1969 (poster).
- Kefalov, V.J., Cornwall, M.C., and Crouch, R.K. (1998). β-Ionone activates phototransduction in a bleach-adapted salamander rod photoreceptor cell. IOVS 39: 5171 (paper).