We would like to congratulate Philip Williams, PhD on receiving a grant for his groundbreaking research on the neuromodulatory potential of primary cilia. This grant, funded by The McDonnell Center for Cellular and Molecular Neurobiology, recognizes the innovative nature of Dr. Williams’ work, which aims to unravel the complex signaling mechanisms within primary cilia and their impact on neuronal circuits and behavior.
Philip Williams, PhD
Assistant Professor, Ophthalmology and Visual Sciences
- Email:prwillia@wustl.edu
- Education: Ph.D., Neuroscience, Washington University in St. Louis, MO 2009 | B.S., Interdisciplinary Studies: Neuroscience, University of Florida, Gainesville, FL 2000
- Williams Lab Page
Understanding How Primary Cilia Affect Vision and Behavior
Primary cilia are small, hair-like structures on the surface of cells. These structures play a crucial role in how brain cells communicate with each other. They are packed with various receptors that respond to neurotransmitters and neuropeptides, which are chemicals that help transmit signals in the brain. Despite knowing their importance, we still don’t fully understand the range of signals that these cilia can handle within a single type of retina cell.
The Study’s Goal
- Explore the different types of signals processed by primary cilia in retinal ganglion cells, a specific type of neuron found in the eye.
- Investigate how disrupting these signals in primary cilia affects complex visual behaviors that rely on retinal ganglion cell activity.
This research will provide new insights into how brain cells communicate and how primary cilia contribute to regulating behaviors, enhancing our understanding of brain function and behavior.