We are excited to announce that Dr. Rajendra Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences, will be the keynote speaker at the 14th Annual CWRU/University Hospitals Department of Ophthalmology Research Day 2024. Keynote Presentation by Dr. Rajendra Apte Dr. Apte will be delivering a keynote address titled “Novel Insights […]
Unlocking the Mysteries of Vision: GRC Visual System Development Conference The 2024 Gordon Research Conference (GRC) on Visual System Development, themed “Establishing Form and Function in the Eye and Visual Brain,” took place from May 19 to 24, 2024. This prestigious international scientific gathering will be hosted in a remote location to foster a sense […]
Medical student Wilson Wang and resident physician Maggie Xing, MD, have made significant contributions to the field of ophthalmology with their recent publication in JAMA Ophthalmology “Interventions for Proliferative Vitreoretinopathy,” co-authored with renowned expert Raj Apte, MD, PhD. Their article provides a comprehensive clinical synopsis and educational review of proliferative vitreoretinopathy (PVR), a serious complication […]
In a significant leap forward for neurodegenerative disease research, Retina fellow Aaditya Shah, MD has published an excellent study titled, “Dark Adaptometry and Optical Coherence Tomography Angiography in Huntington Disease.” This pioneering research is among the first to indicate that retinal biomarkers may be present in patients with Huntington Disease (HD), offering a potentially transformative […]
We are excited to share a new article by Ying-Bo Shui, Ying Liu, Andrew J. W. Huang & Carla J. Siegfried, titled “SDPR Expression in Human Trabecular Meshwork and Its Potential Role in Racial Disparities of Glaucoma,” has been published online in the journal Scientific Reports. This significant research highlights the molecular differences in gene […]
We’re thrilled to announce that Dr. Shiming Chen has been awarded a Seed grant from the Center of Regenerative Medicine for her groundbreaking project titled “hiPSC-induced retinal organoids modeling CRX-linked retinopathies.” This pioneering research aims to establish three-dimensional retinal organoids—essentially human retinas in a dish—to model inherited retinal diseases (IRDs) linked to the cone-rod-homeobox (CRX) […]
The Association for Research in Vision and Ophthalmology (ARVO) is at the forefront of advancing global research aimed at unraveling the complexities of the visual system and combatting its disorders. From May 5th to May 9th, visionaries and experts congregated in Seattle, Washington, for the ARVO 2024 Annual Meeting, a pivotal event showcasing the latest […]
The field of pediatric ophthalmology and strabismus continues to evolve, driven by dedicated professionals committed to enhancing the quality of eye care for children and adults alike. One prominent organization at the forefront of these efforts is the American Association for Pediatric Ophthalmology and Strabismus (AAPOS). With a mission centered on advancing care, supporting education, […]
Congratulations to WashU Ophthalmology Resident, Matt Elitt, MD, PhD and Case Western Reserve’s Tesar Lab colleagues, on the advancement of ION356 to a phase I human clinical trial. Dr. Elitt’s doctoral research published in Nature demonstrated a novel method to pharmacologically target the pathology of Pelizaeus-Merzbacher disease (PMD), representing the first potential treatment option for patients and […]
We are thrilled to announce the publication of a groundbreaking study titled “LXR/CD38 Activation Drives Cholesterol-Induced Macrophage Senescence and Neurodegeneration via NAD+ Depletion“, authored by Ryo Terao, MD, PhD; Mitsukuni Yoshida, MD, PhD; Rajendra Apte, MD, PhD; and colleagues from the Apte Lab. In this study, our researchers unveil critical molecular mechanisms linking dysregulated cholesterol […]
We are thrilled to announce Charles Pfeifer as the distinguished recipient of the highly acclaimed 2024 Dr. Philip Needleman Pharmacology Award. This honor is bestowed upon a graduating student who has exhibited exceptional accomplishments in the field of Pharmacology. Founded in 1991 by Ms. Sima Needleman in tribute to her husband’s unwavering dedication to scholarship […]
Age-related macular degeneration (AMD) is a prevalent eye disease that affects millions of individuals aged 60 and older. Understanding the pathogenesis and developing effective treatments for this condition is crucial. In honor of Dr. Roger H. Johnson, an accomplished ophthalmologist and his dedication to advancing AMD research, the Roger H. Johnson Award was established. This […]
Apply Now for the Winston Fellow Award for Postdoctoral Fellows The Winston Fellow Award Program recognizes outstanding contributions to vision science. The ITVS Pathway overcomes boundaries between disciplines to develop a unique set of basic science, translational and professional skills that will position students to produce transformative breakthroughs in vision science. Students enrolled in the […]
We are thrilled to share with you a remarkable article titled “Retinal Detachment: Causes, Diagnosis, and Treatment Options” co-authored by Rajendra S. Apte, MD, PhD. This enlightening study, published in the renowned journal Nature, explores the intricate details of retinal detachment, providing valuable insights into its causes, diagnosis methods, and available treatment options. In this […]
We are excited to announce that Dr. Margaret Reynolds, a distinguished pediatric ophthalmologist at Washington University in St. Louis, has recently been awarded a grant from the Autism Science Foundation. This one-year grant, starting on February 1st, 2024, aims to explore the potential benefits of vision correction through refractive surgery for children with profound autism. […]
Dr. Margaret M. Reynolds, a renowned researcher at Washington University, has recently been awarded an internal CTRFP grant titled “Phenotype After Refractive Surgery for Autism Spectrum Disorder.” This grant aims to support innovative research projects that can translate scientific discoveries into tangible improvements in human health. The grant, administered by the Institute of Clinical and […]
Precise and targeted healthcare interventions are invaluable in ensuring better outcomes for patients. Investing in innovative research to uncover biomarkers and personalized treatment approaches is at the heart of precision health. In this regard, we are pleased to highlight Dr. Walsh‘s recent achievement of receiving an internal grant from the ICTS – Precision Health Innovation […]
Graduate student Tim Lee from the Division of Biology and Biomedical Sciences (DBBS), working in collaboration with the Apte Lab, has published a new paper revealing a significant discovery in the realm of photoreceptor dysfunction. The research, titled “Identification of IMPDH as a Therapeutically Modifiable Target of AMP Kinase in Rod Photoreceptors,” sheds light on […]
Congratulations to MSTP Student Joseph Lin on Collaborative Breakthrough Publication in Cell Reports Medicine: Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration The Apte Lab is proud to announce the groundbreaking collaborative research publication by MSTP student Joseph Lin and the Ruzycki Lab. The study, published in Cell Reports Medicine, addresses age-related macular […]
Congratulations to Dr. Mitsukuni Yoshida from the Apte lab, who has been chosen by the American Society for Clinical Investigation (ASCI) as an Emerging-Generation (E-Gen) Awardee. The ASCI acknowledges post-MD, pre-faculty appointment physician-scientists actively involved in immersive research, providing them with access to the ASCI joint meeting and longitudinal programming over a 2-year period. Mitsu […]