Welcome to Ophthalmology Clinical Trials
Along with treatment in our ophthalmology clinics, we are also actively involved in clinical research studies.
These studies are varied and can be sponsored by industry, the national institutes of health (NIH), private foundation or by our department.
Studies are led by a faculty member who has an interest in the condition.
Frequent Questions on Clinical Trials
What is a Clinical Trial?
Clinical trials, also known as research studies or patient studies, are essential in the fight against disease. They determine if new treatments are safe and effective and work better than current treatments. By taking part in an ophthalmology clinical trial, you are adding to our knowledge about eye disease and help improve future treatment.
Why Should I participate in a clinical Trial?
The National Institutes of Health (NIH) has a complied information on what a clinical trial is and why they are important https://www.nih.gov/health-information/nih-clinical-research-trials-you
How am I protected?
Each study goes through a rigorous internal review process.
This will be explained in the consent form you will be asked to sign if you want to participate in a study.
I am interested in participating – how do I find a trial?
There are several ways;
- Contact our clinical trial team to see what we are currently involved in
- Join Washington University’s Research Participant Registry and be matched to ongoing studies
- Check out ClinicalTrials.gov – this is a database of privately and publicly funded clinical studies conducted around the world
Ongoing Clinical trials
Please contact our clinical trials team is you are interested in participating in any of these trials. Please note that this list is not exhaustive and is subject to change.
Industry Sponsored
- Regenera RPh201 study – Gregory Van Stavern MD – to study the efficacy and safety of twice-weekly subcutaneous administration of RPh201 over 26 weeks on visual function in participants with prior nonarteritic anterior ischemic optic neuropathy (NAION)
- LEROS study – Gregory Van Stavern MD – to study the efficacy and safety of Raxone (Idebenone) in Lebers hereditary optic neuropathy (LHON) patients.
- CHAMP Study – James Hoekel OD – to determine if the study eye drop can slow the progression of myopia in children.
- LUMINA study – Lynn Hassman MD, PhD – to assess the efficacy and safety of DE-109 440 µg every 2 months in subjects with active, non-infectious uveitis of the posterior segment of the eye.
- XEN45 study – Arsham Sheybani MD/ Anjali Bhorade MD – to compare the effectiveness and safety of XEN to trabeculectomy in subjects with open angle glaucoma refractory to topical medical therapy
Federally sponsored
- ZEDS study – Andrew Huang MD, M.P.H- to determine whether prolonged suppressive oral antiviral treatment with valacyclovir reduces complications of Herpes Zoster Ophthalmicus