Welcome to Ophthalmology Clinical Trials

Along with treatment in our ophthalmology clinics, we are also actively involved in clinical research studies.

These studies are varied and can be sponsored by industry, the national institutes of health (NIH), private foundation or by our department.

Studies are led by a faculty member who has an interest in the condition.

Meet our clinical trials team

Our clinical trials office is located at the center for outpatient health within the ophthalmology clinic.

For appointments or other questions on ophthalmology clinical trials, please email DOVSClinicalResearch@wustl.edu

If you have any questions on the clinical trials listed below, please contact our coordinators

Eve Adcock    adcockl@wustl.edu

Sandra Quirin squirin@wustl.edu

Amer Al Badawi aamer@wustl.edu

Jolene Brasher bjolene@wustl.edu

For research billing and contract questions, please contact Shonda McDaniel shonda@wustl.edu

Frequent Questions on Clinical Trials

What is a Clinical Trial?

Clinical trials, also known as research studies or patient studies, are essential in the fight against disease. They determine if new treatments are safe and effective and work better than current treatments.  By taking part in an ophthalmology clinical trial, you are adding to our knowledge about eye disease and help improve future treatment.

Why Should I participate in a clinical Trial?

The National Institutes of Health (NIH) has a complied information on what a clinical trial is and why they are important  https://www.nih.gov/health-information/nih-clinical-research-trials-you

How am I protected?

Each study goes through a rigorous internal review process. This will be explained in the consent form you will be asked to sign if you want to participate in a study.

I am interested in participating – how do I find a trial?

There are several ways;

Ongoing Clinical trials

Please contact our clinical trials team if you are interested in participating in any of these trials.  Please note that this list is not exhaustive and is subject to change.

Industry Sponsored

  • TEPEZZA (HZNP-TED-403) study – Steven Couch MD – to investigate the efficacy, safety and tolerability of TEPEZZA in participants with chronic (inactive) TED (Thyroid Eye Disease)
  • TEPEZZA (HZNP-TED-402) study – Steven Couch MD – to evaluate the safety and tolerability of different dosing durations of TEPEZZA.
  • TEPEZZA (HZNP-TED-103) study – Steven Couch MD – to evaluate the safety and tolerability of a single subcutaneous dose of TEPEZZA
  • Dextenza CLN-0050 Study – Lawrence Tychsen MD – a study assessing the safety and efficacy of Dextenza for the treatment of ocular pain and inflammation following surgery for pediatric cataract.
  • ShORe (OPT-302) study – Kisha Piggott MD, PhD – to evaluate the efficiacy and safety of intravitreal OPT-302 in combination with Ranibizumab, compared to Ranibizumab alone in partipants with nAMD

Federally sponsored

  • ADVISE study – Lynn Hassman MD, PhD – Multicenter randomized parallel-treatment, comparitive effectiveness trial comparing Adalimumab vs. conventional immunosuppression for uveitis