Siegfried Lab

Carla Siegfried, MD, Jacquelyn E. and Allan E. Kolker, MD, Distinguished Professor of Ophthalmology and Visual Sciences

 Dr. Siegfried’s profile


Glaucoma: The diagnostic and therapeutic assessment of glaucoma, including pharmacological, surgical, and laser treatment, patient support and decision making models in glaucoma.


View all Carla Siegfried’s NCBi publications on PubMed

GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients Ban, N., Siegfried, C. J., Lin, J. B., Shui, Y. B., Sein, J., Pita-Thomas, W., Sene, A., Santeford, A., Gordon, M., Lamb, R., Dong, Z., Kelly, S. C., Cavalli, V.Yoshino, J. & Apte, R. S., May 4 2017, In : JCI Insight. 2, 9

Expression profiling of ascorbic acid-related transporters in human and mouse eyes Ma, N., Siegfried, C., Kubota, M., Huang, J., Liu, Y., Liu, M., Dana, B., Huang, A., Beebe, D., Yan, H. & Shui, Y. B., Jun 2016, In : Investigative Ophthalmology and Visual Science. 57, 7, p. 3440-3450 11 p.

Mitochondrial oxygen metabolism in primary human lens epithelial cells: Association with age, diabetes and glaucoma Kubota, M., Shui, Y. B., Liu, M., Bai, F., Huang, A. J., Ma, N., Beebe, D. C. & Siegfried, C. J., Aug 1 2016, In : Free Radical Biology and Medicine. 97, p. 513-519 7 p.

Preserve the (intraocular) environment: The importance of maintaining normal oxygen gradients in the eye Beebe, D. C., Shui, Y. B., Siegfried, C. J., Holekamp, N. M. & Bai, F., May 2014, In : Japanese Journal of Ophthalmology. 58, 3, p. 225-231 7 p.

Randomized, prospective, comparative trial of ex-press glaucoma filtration device versus trabeculectomy (XVT Study) Netland, P. A., Sarkisian, S. R., Moster, M. R., Ahmed, I. I. K., Condon, G., Salim, S., Sherwood, M. B. & Siegfried, C. J., Feb 2014, In : American journal of ophthalmology. 157, 2, p. 433-440.e3

Aqueous humor oxygen measurements Nguyen, A., Shui, Y. B., Zhang, Q., Beebe, D. C. & Siegfried, C. J., Oct 1 2013, In : Journal of Glaucoma. 22, 8, p. e23-e24

The development of a decision analytic model of changes in mean deviation in people with glaucoma: The COA model Kymes, S. M., Lambert, D. L., Lee, P. P., Musch, D. C., Siegfried, C. J., Kotak, S. V., Stwalley, D. L., Fain, J., Johnson, C. & Gordon, M. O., Jul 1 2012, In : Ophthalmology. 119, 7, p. 1367-1374 8 p.

Racial differences in ocular oxidative metabolism: Implications for ocular disease
Siegfried, C. J., Shui, Y. B., Holekamp, N. M., Bai, F. & Beebe, D. C., Jul 1 2011, In : Archives of Ophthalmology. 129, 7, p. 849-854 6 p.

Vitreoretinal influences on lens function and cataract Beebe, D. C., Holekamp, N. M., Siegfried, C. & Shui, Y. B., Apr 27 2011, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 366, 1568, p. 1293-1300 8 p.