Florentina Soto, PhD

Florentina Soto, PhD

Associate Professor, Ophthalmology and Visual Sciences


Retina, Retinal Degenerations & Neovascularization (Physiology)

Research Interests »


  • MS: Biochemistry, University of Murcia, Spain, 1988
  • PhD, Neurosciences, Institute of Neuroscience and Medical School, University of Alicante, Spain, 1992


  • Fellow: Center for Molecular Neurobiology, Hamburg, Germany (1992-1995) and Max-Planck Institute for experimental Medicine, Goettingen, Germany, 1995-1998

Selected Publications

  1. Nicke, A., Kuan, Y.H., Masin, M., Bender, O., Rettinger, J., Marquez-Klaka, B., Górecki, D.C., Murrell-Lagnado, R., and Soto, F. (2009) A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 KO mice. Journal of Biological Chemistry, 284:25813-25822.
  2. Kucenas, S., Soto, F., Cox, J.A. and Voigt, M.M. (2006) Selective labeling of central and peripheral sensory neurons in the developing zebrafish using P2X(3) receptor subunit transgenes. Neuroscience 138:641-652.
  3. Masin M., Kerschensteiner D., Dümke K., Rubio M.E., Soto F. (2006) Fe65 interacts with P2X2 subunits at excitatory synapses and modulates receptor function. Journal of Biological Chemistry 281:4100-4108.
  4. Nicke, A, Kerschensteiner, D. and Soto, F. (2005) Biochemical and functional characterization of the heteromeric receptor formed by P2X1 and P2X4 subunits. Journal of Neurochemistry, 92, 925-933.
  5. Ruppelt, A., Ma, W., Borchardt, K., Silberberg, S.D. and Soto, F. (2002) Genomic structure, developmental distribution and functional properties of the chicken P2X5 receptor. Journal of Neurochemistry, 77, 1256-1265.
  6. Rubio, M. E. and Soto, F. (2001) Distinct localization of P2X receptor at excitatory postsynaptic specializations. Journal of Neuroscience, 21, 641-653.