Tag: Kerschensteiner Lab

Genome-wide screen yields new gene therapies to protect against retinal degeneration (Links to an external site)

Researchers in the WashU Medicine John F. Hardesty, MD, Department of Ophthalmology & Visual Sciences have discovered key neuroprotective genes that could lead to the development of gene therapies to treat retinitis pigmentosa, an inherited form of retinal degeneration that causes blindness. The findings, published in Neuron April 9, point to new therapeutic strategies to maintain retinal health and protect against […]

Evolutionarily Conserved Pupil Response Sharpens Image Quality to Improve Visual Acuity 

Evolutionarily Conserved Pupil Response Sharpens Image Quality to Improve Visual Acuity 

This Research Insight covers a publication from the Kerschensteiner Lab. Here, we highlight how Michael Fitzpatrick, PhD and colleagues uncovered a new pupil response in the mouse, disentangled the neural pathway in the retina that drives it, and discovered that it is also present in humans. These findings shed new light on strategies the visual […]

The Role of Direction-Selective Signaling in Predation

This Research Insight covers a recent publication from the Kerschensteiner Lab. Here, we highlight how Jenna Krizan, PhD and colleagues added clarity to an ongoing debate about the origin of direction-selective signaling in the brain and explored its role in the predatory behaviors of the mouse. In their recent paper published in PNAS, scientists in […]