This Research Insight covers a collaborative study pioneered by the Yoshimatsu Lab, which elucidates a rod photoreceptor-driven pathway in the zebrafish retina that supports dim-light vision and is shared across species. Whereas the rod pathway has been speculated to be unique to the mammalian retina, this study presents the first converging evidence that a homologous […]
This Research Insight covers a publication from the Kerschensteiner Lab. Here, we highlight how Michael Fitzpatrick, PhD and colleagues uncovered a new pupil response in the mouse, disentangled the neural pathway in the retina that drives it, and discovered that it is also present in humans. These findings shed new light on strategies the visual […]
This Research Insight covers a recent publication from the Siegfried Lab. Here, we highlight how Ying-Bo Shui, MD, PhD and colleagues identified a gene that might exacerbate the worse primary open-angle glaucoma presentation experienced by Black individuals. In their recent paper published in Scientific Reports, scientists in the lab of Carla Siegfried, MD, professor of […]
This Research Insight covers a recent publication from the Apte Lab. Here, we highlight how Ryo Terao, MD, PhD, Mitsukuni Yoshida, MD, PhD, and colleagues explore how excessive cholesterol accumulation in the retina contributes to the degeneration of light-sensing photoreceptors, leading to vision loss. The evidence presented in this study suggests that targeting a process […]
This Research Insight covers a recent publication from the Kerschensteiner Lab. Here, we highlight how Jenna Krizan, PhD and colleagues added clarity to an ongoing debate about the origin of direction-selective signaling in the brain and explored its role in the predatory behaviors of the mouse. In their recent paper published in PNAS, scientists in […]
This Research Insight covers a recent publication from the Morgan Lab. Here, we highlight the stand-out performance of a modified deep learning-based tool to assess the quality of electron micrographs in real-time. In their recent paper published in Microscopy and Microanalysis, scientists in the lab of Joshua Morgan, PhD, assistant professor of ophthalmology at WashU […]