Rajendra Apte, MD, PhD, Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences
Innate immunity and immune effector mechanisms in the retina; oxidative stress and cell death; models of developmental angiogenesis and neovascularization; inflammation and photoreceptor survival; macular degeneration
Shiming Chen, PhD, Professor, Ophthalmology and Visual Sciences Professor, Developmental Biology
The major goal of our laboratory research is to identify the molecular mechanism(s) regulating photoreceptor gene expression in the mammalian retina and the implications of these mechanisms for understanding photoreceptor degenerative diseases and developing therapeutic treatments for these diseases.
Joseph Corbo, MD, PhD, Associate Professor, Pathology & Immunology
We are interested in the transcriptional regulatory networks that underlie the development, evolution, and diseases of photoreceptors in the retina. We are taking a multi-disciplinary approach to the problem of how a network of transcription factors orchestrates the expression of distinct cohorts of downstream genes to build this complex micromachine, the photoreceptor cell.
Daniel Kerschensteiner, MD, Professor, Ophthalmology and Visual Sciences; Professor, Neuroscience; Professor, Biomedical Engineering
We would like to understand the principles that guide the assembly of neural circuits and to decipher the way they process information. Our efforts concentrate on the mammalian retina.