New Study Reveals Role of Autophagy in Protecting Vision

New Study Reveals Role of Autophagy in Protecting Vision

Autophagy Regulates Müller Glial Cell Inflammatory Activation A new study published in Investigative Ophthalmology & Visual Science highlights the critical role of autophagy—the body’s process of recycling proteins—in regulating inflammation within the retina. The research, led by Thomas Ferguson, PhD, and Philip Ruzycki, PhD, from the John F. Hardesty, MD, Department of Ophthalmology & Visual […]

Linking Ocular Hypertension and Primary Open-Angle Glaucoma: What We Can Do About It

Linking Ocular Hypertension and Primary Open-Angle Glaucoma: What We Can Do About It

This Research Insight covers a series of studies supported by Mae Gordon, PhD and Michael Kass, MD that highlights the impact of a long-term clinical study, the Ocular Hypertension Treatment Study (OHTS). Together, this research—spanning more than 20 years—has revolutionized the diagnosis of primary open-angle glaucoma (POAG), its treatment, and patient outcomes. In this series […]

Will I Need Reading Glasses After LASIK Surgery? | St. Louis LASIK at WashU Medicine LASIK Surgery Center

Will I Need Reading Glasses After LASIK Surgery? | St. Louis LASIK at WashU Medicine LASIK Surgery Center

One of the most common questions we hear from patients considering LASIK is: “Will I still need reading glasses afterward?” Stephen Wexler, MD, LASIK surgeon at WashU Medicine LASIK Surgery Center, explains that the answer depends largely on your age and your vision goals. Under 40: Freedom From Glasses If you’re under 40 and choose […]

Featured Fellows and Residents Spotlight: Jessica Sun, MD

Featured Fellows and Residents Spotlight: Jessica Sun, MD

This spotlight series highlights the individuals behind the white coats, their journeys, passions, and the impact they’re making in the field of medicine. Today, we highlight Jessica Sun, MD. Incoming Resident: Jessica Sun, MD Where are you from? Montreal, Canada and Potomac, Maryland Where did you attend Medical School? Harvard Medical School Favorite memory of […]

Study Explores Effects of S1P Receptor Modulation on the Retina

Study Explores Effects of S1P Receptor Modulation on the Retina

St. Louis, MO — August 27, 2025 — Researchers at the WashU Medicine John F. Hardesty, MD, Department of Ophthalmology & Visual Sciences in collaboration with the Department of Neurology have published new findings on the effects of sphingosine-1-phosphate (S1P) receptor modulation on the human retina. The study, led by the Apte Lab and published […]

Margret Reynolds, MD, Receives Prestigious NIH K23 Award for Groundbreaking Research on Refractive Surgery in Autism Spectrum Disorder

Margret Reynolds, MD, Receives Prestigious NIH K23 Award for Groundbreaking Research on Refractive Surgery in Autism Spectrum Disorder

St. Louis, MO – August 26, 2025 – John F. Hardesty, MD, Department of Ophthalmology & Visual Sciences at WashU Medicine is proud to announce that Margret Reynolds, MD, has been awarded a highly competitive K23 Mentored Patient-Oriented Research Career Development Award from the National Institutes of Health (NIH). This award supports early-career clinician-scientists who […]

Welcome Alexander Lyss, OD

Welcome Alexander Lyss, OD

The John F. Hardesty, MD, Department of Ophthalmology & Visual Sciences at WashU Medicine welcomes Alexander Lyss, OD, to the clinical team. Lyss brings a unique background and a strong commitment to patient-centered eye care. Before pursuing optometry, Lyss worked as a chemist—but soon realized he wanted a career that allowed him to connect more […]

New Publication: Rethinking How We Quantify Effects in Cell Biology

New Publication: Rethinking How We Quantify Effects in Cell Biology

We’re excited to share a new publication from Josh Morgan, PhD, Assistant Professor, Ophthalmology and Visual Sciences, titled “Alternative to the statistical mass confusion of testing for ‘no effect’”, published in the July 2025 issue of the Journal of Cell Biology. Morgan’s work challenges the traditional reliance on P values to determine whether an effect exists. While P […]

Featured Fellows and Residents Spotlight: Kathryn Flaharty, MD

Featured Fellows and Residents Spotlight: Kathryn Flaharty, MD

This spotlight series highlights the individuals behind the white coats, their journeys, passions, and the impact they’re making in the field of medicine. Today, we highlight Kathryn Flaharty, MD. Incoming Resident: Kathryn Flaharty, MD Where are you from? Fort Myers, Florida Where did you attend Medical School? University of Michigan Medical School Favorite memory of […]

Groundbreaking Study Reveals How lncRNA Evf2 Guides Forebrain Interneuron Development

Groundbreaking Study Reveals How lncRNA Evf2 Guides Forebrain Interneuron Development

AUGUST 2025 – ST. LOUIS, MO — Brian Clark, PhD Assistant Professor, Ophthalmology and Visual Sciences, and colleagues have published a new study titled “Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA–enhancer gene guidance through direct RNA binding and RNP recruitment domains”. This work provides new insights into how long non-coding RNAs (lncRNAs) […]

Science in Focus: Art Beyond the Microscope

Science in Focus: Art Beyond the Microscope

Science in Focus: Art Beyond the Microscope, a science as art competition! We invite all vision science researchers to participate in this unique competition, where science and art intersect to reveal the beauty within scientific research. Purpose and Goals Our goal is to celebrate the beauty of science and engage the community in its impact. […]

Understanding Uveitis: Causes, Treatments & Hope for the Future

Understanding Uveitis: Causes, Treatments & Hope for the Future

Uveitis might sound like a rare eye condition, but it affects thousands of people each year—causing discomfort, vision problems, and concern for long-term eye health. If you’ve recently been diagnosed or are supporting a loved one with uveitis, here’s what you need to know about the condition, its causes, treatment options, and why there’s real […]

Featured Fellows and Residents Spotlight: Olivia Cummings, MD, MSc

Featured Fellows and Residents Spotlight: Olivia Cummings, MD, MSc

This spotlight series highlights the individuals behind the white coats, their journeys, passions, and the impact they’re making in the field of medicine. Today, we highlight Olivia Cummings, MD, MSc. Incoming Resident: Olivia Cummings, MD, MSc Where are you from? New York Where did you attend Medical School? The Warren Alpert Medical School of Brown […]

July Is Children’s Eye Health & Safety Month: Time to See (and Play) Outdoors!

July Is Children’s Eye Health & Safety Month

July isn’t just summer vacation—it’s also  Children’s Eye Health & Safety Month! At WashU Medicine’s John F. Hardesty, MD, Department of Ophthalmology & Visual Sciences, we’re highlighting the crucial role of sunshine and outdoor play in promoting healthy vision, particularly in preventing nearsightedness (myopia). Here’s a deep dive into the latest insights from the American […]

Featured Fellows and Residents Spotlight: Krishna Mallem, MD

Featured Fellows and Residents Spotlight: Krishna Mallem, MD

This spotlight series highlights the individuals behind the white coats, their journeys, passions, and the impact they’re making in the field of medicine. Today, we highlight Krishna Mallem, MD. Incoming Resident: Krishna Mallem, MD Where are you from? Plainsboro, New Jersey Where did you attend Medical School? Drexel University College of Medicine Favorite memory of […]

First-of-Its-Kind Apte Lab Study Links Retinal Microglia to Circadian Rhythms

First-of-Its-Kind Apte Lab Study Links Retinal Microglia to Circadian Rhythms

A Novel Insight Into Eye Immunity and Circadian Biology Charles Pfeifer, PhD, a former graduate student and postdoctoral researcher, Andrea Santeford, MS, supervisor in the Apte Lab at WashU Medicine, and Rajendra Apte, MD, PhD, Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences, have published a landmark study in the journal Glia. The paper, […]

2025 Graduation Awards Ceremony

2025 Graduation Awards Ceremony

WashU Medicine’s John F. Hardesty Department of Ophthalmology and Visual Sciences proudly celebrated the achievements of its outstanding students, residents, fellows, and faculty during the 2025 Graduation Awards Ceremony, held on Saturday, June 21. Hosted by Department Chair Todd Margolis, MD, PhD, the ceremony highlighted the academic and clinical accomplishments of the Class of 2025, […]

Are You Sleeping in Your Contacts? Here’s Why That’s a Bad Idea—Especially If You’re Considering LASIK

Are You Sleeping in Your Contacts? Here’s Why That’s a Bad Idea

Click below to hear Eric Polk, OD from WashU Medicine LASIK Surgery Center explain why sleeping in your contacts can affect your LASIK candidacy: Why It Matters: Contacts, Sleep, and LASIK Risks Raise your hand if you’ve ever accidentally fallen asleep in your contacts. You’re definitely not alone! But as Eric Polk, OD explains in […]

Residents and Fellows Spotlight: Deena Shaath, MD

Residents and Fellows Spotlight: Deena Shaath, MD

This spotlight series highlights the individuals behind the white coats, their journeys, passions, and the impact they’re making in the field of medicine. Today, we highlight Deena Shaath,MD. Graduating Fellow: Deena Shaath, MD What are your future plans? I’m moving to Orlando for a private practice job! Why did you choose Ophthalmology and Cornea? Ophthalmology […]

Yoshida Named 2025 NIH Outstanding Scholar in Neuroscience

Yoshida Named 2025 NIH Outstanding Scholar in Neuroscience

JULY 3, 2025 — ST. LOUIS, MO — WashU Medicine John F. Hardesty, MD Department of Ophthalmology and Visual Sciences congratulates Mitsukuni Yoshida, MD, PhD, on being selected as a 2025 recipient of the NIH Outstanding Scholars in Neuroscience Award Program (OSNAP). I am very humbled and honored to receive this recognition. As a physician-scientist, […]